Research Grants

Abiomed funds research programs that investigate how mechanical circulatory support with Impella® heart pumps may improve patient outcomes.

All types of research programs will be considered, including but not limited to: clinical studies and pre-clinical investigations. All research programs must focus on how Impella support can improve patient outcomes. Research proposals are reviewed quarterly by Abiomed's academic research department. The deadline for submission to each of these quarterly review sessions is outlined below.

Areas of Interest

The following research domains have been identified by Abiomed to be areas of interest for innovation within the field. Applications within these domains will be given priority in the competitive application process. However, applications outside these domains will still be considered.

Best Practices in Urgent Patient Populations

  • Maximizing procedural, acute and long-term benefits while minimizing complication risks (ie. peripheral vascular complications and acute limb ischemia) for patients supported during urgent cases, including but not limited to: NSTEMI, CTO, peripartum cardiomyopathy and ECPR.
  • Exploring methods to guide how Impella can minimize time to treatment and escalation in critical cardiac situations for improved patient outcomes.
  • Exploring Alternatives to Heparin and A/C monitoring, including PPT and Anti-Xa guidance.

Impella Support for Heart Recovery

  • Use of Impella 5.5® with SmartAssist® for reverse remodeling and recovery, including mechanisms of action, adjunctive therapies, right heart failure, outcomes, best practices for patient management and prediction of patient recoverability.
  • Determining optimal duration of Impella support and weaning in Acute Myocardial Infarction with Cardiogenic Shock (AMI-CGS) and implications on both short-term and long-term patient recovery.
  • Utilizing artificial intelligence to predict recovery and enhance decision-making processes in Impella-supported cases, focusing on AI Digitization to improve the prediction of patient outcomes.

Impella as a Platform to Enable Cardiac Interventions in High-Risk Populations

  • Use of Impella in surgical and interventional procedures for pre-procedure optimization, BTT, BTR, or prevention of PCCS, including patient identification, timing of support, patient management.

End Organ Protection with Impella

  • Identification of patients at risk for cardiorenal or other end organ dysfunction and unmasking the mechanisms of organ-to-heart crosstalk.
  • Impact of Impella support on acute or chronic end organ dysfunction to improve patient outcomes.

Instructions for Grant Submission:

To submit a research grant request, enter relevant study information into the research grant and itemized budget templates and upload online for submission.

A research grant submission is required to contain the following attachments:

  1. Proposal
  2. Itemized budget
  3. Principal investigator CV, including list of study-related publications.

 

Optional & recommended documents:

  1. Figures and tables
  2. Cover letter
  3. Documentation identifying requestor's status as a non-profit, charitable organization
  4. Other relevant documents

 

Completed applications received by the quarterly deadline will be reviewed at the next available proposal review session. If you have any questions regarding this process, or would like to speak to a member of our academic research department regarding your new or existing application, please contact us at [email protected].

Quarterly Review Dates for 2023 and 2024:

Quarterly deadline for submission/resubmission of grant proposal Proposal review session (week of) PI notified of result of review by
August 21, 2023 September 4, 2023 October 2, 2023
November 20, 2023 December 4, 2023 January 8, 2024
February 26, 2024 March 4, 2024 April 1, 2024
May 20, 2024 June 3, 2024 July 1, 2024

Begin Application

NPS-2029