Cost-Effectiveness and Reimbursement
Growing Crisis of Coronary Artery Disease and Heart Failure
-
>15M
people with coronary artery disease (CAD) and more than 875,000 deaths per year from CAD2
-
65+
year-old population expected to increase an additional 44% by 2030. Mortality also increasing in 45-65 year-old population3
-
~50%
cardiogenic shock mortality rate for last 20+ years4 without Impella heart pumps
Impella is Associated with Reduced Mortality and Cost
Legacy studies on previous generations of Impella pumps showed the use of percutaneous ventricular assist devices (PVADs), including Impella, is particularly cost-effective.
- 29-47% reduction in adverse events at 90 days (death, stroke, MI, and/or repeat revascularization)5, 6
- 58% reduction in 30-day mortality for patients with CAD7
- 44% lower in-hospital mortality for patients with higher comorbidities vs. IABP8
Impella Reduces Length of Stay and Readmissions
Impella therapy demonstrates significant cost savings and cost-effectiveness for payers and providers
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Additional Resources
References
- Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. (2019). Circulation.
- Einarson, et al. (2018). Cardiovasc Diabetol. 17, 83.
- Sidney, S., Go, A. S., Jaffe, M. G., Solomon, M. D., Ambrosy, A. P., & Rana, J. S. (2019). Association between aging of the US population and heart disease mortality from 2011 to 2017. JAMA Cardiology, 4(12), 1280-1286.
- Jeger, et al. (2008). Ann Intern Med.
- O’Neill, W.W., et al. (2012). Circulation, 126(14), 1717-1727.
- Dangas, G.D., et al. (2014). Am J Cardiol, 113(2), 222-228.
- Stretch, R., et al. (2014). J Am Coll Cardiol, 64(14), 1407-1415.
- Al-Khadra, et al. (2019). CCI, 95(3), 503-512.
- Maini, B., et al. (2014). Expert Rev Pharmacoecon Outcomes Res, 14(3), 403-416.
- Gregory, D., et al. (2013). Am Health Drug Benefits, 6(2), 88-99.
- Aryana A, et al. Heart Rhythm. 2014;11(7):1122-1130.
- Wohns D, et al. Innovations (Phila). 2014;9(1):38-42.
- Maini B, et al. Catheter Cardiovasc Interv. 2014;83(6):E183-E192.
- Cheung A, et al. J Am Coll Cardiol. 2012;60(17 Suppl B):B110. Abstract TCT-385
NPS-1282