A New Standard of Care for Acute Right Heart Failure
Fully Intracorporeal Right Heart MCS Device Designed for Ease of Delivery and Quick Stabilization
The Impella RP Flex™ with SmartAssist® heart pump has the ability to stabilize hemodynamics, unload the right ventricle and allow for native heart recovery in patients with right ventricular dysfunction. Delivered through a minimally- invasive catheterization technique via the right femoral or right IJ vein, Impella RP Flex™ with SmartAssist® is designed to provide the flow and pressure needed to compensate for right heart dysfunction. The RECOVER RIGHT study demonstrated that the Impella RP® increased cardiac index and reduced central venous pressure immediately after pump implementation and led to sustained hemodynamic improvement.
Early detection and management of RVD is associated with improving outcomes in AMICS patients who develop RVF/Acute Right Heart Failure
RVD in AMICS is associated with increased mortality
Why RP Flex?
- Rapid deployment of RV and LV Impella Catheters is clinically feasible and a tool for quick stabilization
- Stabilization with Impella RP is associated with a reduction in inotropes/vasopressors3
- Shah, et al: “Patients treated with pRVAD early, before developing refractory shock and/or ischemic brain injury had favorable mortality compared to historical cohorts” 4
The Impella RP System is indicated for providing temporary right ventricular support for up to 14 days in patients with a body surface area ≥1.5 m2 who develop acute right heart failure or decompensation for less than 48 hours following left ventricular assist device implantation, myocardial infarction, heart transplant, or open-heart surgery, without the presence of profound shock, end organ failure, or acute neurologic injury.
Resources for Health Care Professionals
References
Jain, P. et al. (2021). Right Ventricular Dysfunction Is Common and Identifies Patients at Risk of Dying in Cardiogenic Shock. Journal of cardiac failure, 27(10), 1061–1072. https://doi.org/10.1016/j.cardfail.2021.07.013
Gorgis, S. et al. (2024). Impact of Right Ventricular Dysfunction on Outcomes in Acute Myocardial Infarction and Cardiogenic Shock: Insights from the National Cardiogenic Shock Initiative. Journal of cardiac failure, 30(10), 1275–1284. https://doi.org/10.1016/j.cardfail.2024.07.015
Anderson, M. B. et al. (2015). Benefits of a novel percutaneous ventricular assist device for right heart failure: The prospective RECOVER RIGHT study of the Impella RP device. J Heart Lung Transplant, 34(12), 1549–1560. https://doi.org/10.1016/j.healun.2015.08.018
Shah Y, et al. (2024). Safety And Efficacy Of Impella RP Support For Acute Right Ventricular Failure Complicated By Cardiogenic Shock: Post Market Approval SubAnalysis Of The CVAD Registry. J Card Fail; 30(1):269. https://doi.org/10.1016/j.cardfail.2023.10.361
NPS-1307