Abiomed funds clinical research programs that investigate how mechanical circulatory support with Impella® heart pumps may improve patient outcomes.
All types of research programs will be considered for funding through Abiomed’s Investigator-Sponsored Studies (ISS) office. ISS are clinical studies that are initiated, developed, and conducted by a qualified researcher external to Abiomed who assumes all legal and regulatory responsibility for the trial. Potential ISS programs are funded through a competitive review process.
Areas of Interest
The following research domains have been identified by Abiomed to be areas of interest for innovation within the field. Applications within these domains will be given priority in the competitive application process. However, applications outside these domains will still be considered.
Anticoagulation and Best Practices
Managing procedural and long-term patient anticoagulation, vascular access techniques and patient outcomes or defining optimal anticoagulation for Impella patients and best practices to improve patient outcomes, including maintaining appropriate Impella position during mid- to long-term support
Long Duration Impella Support for Heart Recovery
Use of Impella 5.5® with SmartAssist® for reverse remodeling and recovery, including mechanisms of action, adjunctive therapies, outcomes and best practices for patient management
Studies exploring differential effects of MCS on hemodynamics, clinical outcomes and underlying physiological mechanisms in males and females
Cardiorenal Mechanisms and Renal Protection with Impella
Studies focused on cardiorenal crosstalk or intrarenal mechanisms impacted by Impella support that modulate acute or chronic changes in renal function to improve patient outcomes
Researchers interested in applying to Abiomed for competitive research funding should familiarize themselves with investigator expectations, Abiomed funding priorities, and the research grant review process.
Competitive Review Process
Abiomed carefully evaluates all submitted proposals. The investigator-sponsored studies review board evaluates applications based on the following criteria:
- Scientific and clinical impact
- Alignment with established funding priorities
- Study design and methodology
- Investigator experience & research site infrastructure
- Patient safety
Abiomed and investigators funded through the ISS office share a common goal of generating high quality data, protecting human subjects, complying with all regulatory requirements, and advancing science for human health.
Special consideration will be given to applications investigating inequities and disparities observed in health outcomes.
Investigator-Sponsored Studies Responsibilities
Investigator-Sponsored Study Application Process
1. Submit your complete application
You will be asked to submit an initial concept for review (Part A). If the initial concept is approved by Abiomed, a full study proposal (Part B) will be requested. You will be notified of your proposal status via email.
Please note, only complete applications will be considered for review. Proposals submitted by email will not be considered.
2. Proposal Review & Determination
Initial concept proposals are reviewed on an on-going basis, and full proposals are reviewed quarterly. You will be promptly notified of Abiomed’s grant funding decision via email. If you have any questions regarding the process, or would like to speak to the investigator-sponsored studies program team regarding your new or existing application, please contact us at [email protected].
August 22, 2022
November 21, 2022