AMI Cardiogenic Shock

Clinical Evidence

Key Findings from the National Cardiogenic Shock Initiative Study 1,2,3

  • Identify and support cardiogenic shock early
  • Aggressive down titration of inotropes
  • Identify inadequate left ventricular (LV) support and escalate, if CPO <0.6
  • Identify right ventricular (RV) dysfunction early and support
  • Systematically use right heart catheter (RHC) to guide therapy
Graphic displaying the pathway to class 1 recommendation of Impella use in cardiogenic shock

Impella® Clinical Evidence Pathway to Class I Recommendation

Impella clinical evidence has established safety and effectiveness and validated best practices.

Graphic of clinical evidence supporting improved AMI cardiogenic shock outcomes when unloading pre-PCI

The Procedure

Learn more about femoral access explant techniques and other best practices.


  1. Tehrani, B.N., et al. (2019). JACC, 73, 1659-1669.
  2. Basir, M.B., et al. (2019). Catheter Cardiovasc Interv, 93(7), 1173-1183.
  3. O’Neill, W.W., (2020). TCT Connect 2020