AMI Cardiogenic Shock
Clinical Evidence
AMI Cardiogenic Shock

Clinical Evidence

Key Findings from the National Cardiogenic Shock Initiative Study 1,2,3

  • Identify and support cardiogenic shock early
  • Aggressive down titration of inotropes
  • Identify inadequate left ventricular (LV) support and escalate, if CPO <0.6
  • Identify right ventricular (RV) dysfunction early and support
  • Systematically use right heart catheter (RHC) to guide therapy
Graphic displaying the pathway to class 1 recommendation of Impella use in cardiogenic shock

Impella® Clinical Evidence Pathway to Class I Recommendation

Impella clinical evidence has established safety and effectiveness and validated best practices.

Graphic of clinical evidence supporting improved AMI cardiogenic shock outcomes when unloading pre-PCI

Ongoing and Upcoming Clinical Trials

RECOVER IV Randomized Controlled Trial

Upcoming trial to assess whether Impella pre-PCI is superior to PCI without Impella in patients with AMI cardiogenic shock.

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NCSI Study

Ongoing trial seeking to improve mortality in patients with AMI cardiogenic shock using the NCSI algorithm.

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DanGer Shock Randomized Controlled Trial

Ongoing trial assessing primary outcome of death from all causes at six months with Impella CP® compared to standard of care.

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The Procedure

Learn more about femoral access explant techniques and other best practices.

References

  1. Tehrani, B.N., et al. (2019). JACC, 73, 1659-1669.
  2. Basir, M.B., et al. (2019). Catheter Cardiovasc Interv, 93(7), 1173-1183.
  3. O’Neill, W.W., (2020). TCT Connect 2020

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